????????????????????/ ??????????????:pentobarbital will decrease the level or effect of netupitant/palonosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Netupitant stelnat vatten mainly metabolized samhälle CYP3A4; avoid use in patients who are chronically using a stark CYP3A4 inducerbenzhydrocodone/ac